Healthy ageing – Your choice – Summary

Published : December 4th, 2019

Summary of the White paper “Healthy aging of humans and animals”

Healthy aging of human and animals, from cradle to grave, requires anti-inflammatory diets from new-born into old age to prevent development of low-grade chronic inflammation in the body. Low-grade chronic inflammation characterizes a wide range of chronic conditions such as type 2 diabetes, cardiovascular diseases and metabolic syndrome characterized by high blood pressure, high insulin levels, overweight and high cholesterol levels1. Low-grade chronic inflammation is perceived as a pre-illness that may be growing unnoticed little-by-little every day for several years (animals) or decades (humans), often creating relatively mild daily bothers such as skin rashes, dry skin, muscle and joint problems, sleeping difficulties, and poor concentration, until a clinical lifestyle disease finally emerges, sometimes overnight. The pro-inflammatory, anti-inflammatory and inflammation resolving fatty acids precusors are primarely Arachidonic acid (AA, omega-6), Eicosapentaenoic acid (EPA, omega-3) and Docosahexaenoic acid (DHA, omega-3).

Product development and Food Safety

The healthy aging products Balanstri Omega3+ (humans) and Effektri (animals) are built from the same principles by combining sufficient, balanced and safe amounts of bioactive anti-inflammatories able to adjust any product or diet to become anti-inflammatory. We use only ingredients that are regularly controlled by Eurofins (www.eurofins.com) to be in line with the new and strict European Food Safety Authority (EFSA) limits since 2018 for environmental toxins such as dioxins and dioxin-like PCB’s, heavy metals and others in food and animal feeds. The maximum intake that will never result in any health risk was set at 2 pg TEQ (toxic equivalent) per kg bodyweight per week. The advised daily intake of Balanstri Omega3+ (humans) and Effektri (animals) will never present any health risk for humans or animals, independent of age, race or gender.

Our unique knowledge

A safe, proven method to adjust any product and/or diet to become anti-inflammatory is by balancing, protecting and supporting the fatty acids precursors for pro-inflammatory- and anti-inflammatory tissue hormones formation, as well as the fatty acids precursors for inflammation termination activities in the body. We use ingredients such as marine omega-3 (EPA and DHA), antioxidants from olive (polyphenols), the vitamin E antioxidant and the multifunctional vitamin D being active in both bone formation, immune defense and insulin secretion. Vitamin D deficiency can cause fatigue, muscle and joint pain, weakening of the arms and legs and an increased risk of osteoporosis. Normally, deficiency of vitamin D is due to a diet with little vitamin intake or too little sun exposure. The complementing dried blood spot (DBS) testing technology2 is used as an integrated tool during product development of 1) foods, 2) feeds and 3) dietary food- and feed supplements, to ensure bioavailability of the required precusor fatty acids.

The health benefits of anti-inflammatory diets are:

Prevention of low-grade chronic inflammation from developing in the body.

A pre-illness growing unnoticed little-by-little every day for several years (animals) or decades (humans), creating relatively mild daily bothers such as skin rashes, dry skin, muscle and joint problems, sleeping difficulties, and poor concentration, until a clinical lifestyle disease finally emerges, sometimes overnight.

Maintaining normal blood pressure.

High blood pressure (>140 mm Hg) is globally the main cause of preventable deaths for humans.

Protecting blood cholesterol (LDL) from damage (oxidation).

Components of oxidized blood cholesterol (oxysterols) cause many harmful actions to cell life. Oxidation of blood cholesterol (LDL) in the blood vessel wall is a fundamental step in atherosclerosis.

Easing the flow of red blood cells in narrow capillaries.

Exchange of oxygen (O2) and carbon dioxide (CO2) everywhere in the body is a fundamental step for both physical and mental health.

Restores and maintains an optimal fat metabolism

Fatty acids carry out many functions necessary for normal physiological health of both humans and animals. An optimal fat metabolism prevent daily bothers and support quicker cell and tissue repair, quicker recovery from injuries, stress and tiredness and improve both skin and fur (animals) quality.

Healthy aging food safety – regular safety and oxidative stability analysis

We control our products for the presence of the right amounts of fatty acids and vitamins and for the absence of unwanted environmental contaminants such as dioxins and dioxin-like PCB’s. The advised daily use will never present any risk for humans or animals independent of age, race and gender.

The formulation developed guarantees a full oxidative stability and a stable fatty acid composition

 

1. Minihane, A. M. et. al. 2015. Low-grade inflammation, diet composition and health: current research evidence and its translation. Br. J. Nutr. 2015 Oct 14; 114(7): 999–1012
2. Angela M Rizzo, 2010. A rapid method for determining arachidonic:eicosapentaenoic acid ratios in whole blood lipids: correlation with erythrocyte membrane ratios and validation in a large Italian population of various ages and pathologies. Lipids in Health and Disease 2010,9:7